Sample Protein

Randomly select amino acid residues from a guide sequence with replacement. Generate new sequences of any length based on the amino acid distribution.

Output sequence length

Maximum: 10,000,000 residues

Guide sequence FASTA or raw

residues

Residues will be randomly sampled from this sequence. Each residue can be selected multiple times.

Valid protein sequence

Number of sequences to generate

Generating sampled sequence(s), please wait...

About Sample Protein

Sample Protein randomly selects amino acid residues from a guide sequence with replacement until a sequence of the specified length is constructed.

Use cases

Generate random sequences with specific composition
Monte Carlo simulations
Bootstrap resampling analysis
Null model generation for statistics

vs Shuffle

Sample: any length, with replacement
Shuffle: same length, without replacement
Sample preserves frequency distribution
Shuffle preserves exact composition

How it works

Each residue in the guide sequence has an equal probability of being selected at each position. Since sampling is done with replacement, the same residue can appear multiple times in the output, even if it only appears once in the guide. The output sequence length can be longer or shorter than the guide.

Citations

Stothard P (2000)

The Sequence Manipulation Suite: JavaScript programs for analyzing and formatting protein and DNA sequences.

Biotechniques 28:1102-1104

PubMed

BioChemIntelli

Sample Protein (www.biochemintelli.com)

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